Medication Explained 💊

Paracetamol

I’m going to start a new blog about medications. Covering how they work, what they do in the body, side effects you can possibly experience, how they are metabolised and how they are excreted.

I’m not a Pharmacist or a Doctor. However, I have a degree in Medicinal Chemistry and I have found that my peers have found it beneficial when they ask me about what they have been prescribed. I’m able to put it in to Layman’s terms and not blind with science.

If you have any questions about any medications, I would be more than happy to help.

Paracetamol – One of a group of drugs known as non-opioid analgesics used for mild pain relieve. Taken as directed, for an adult is 500mg-1g every 4-6 hours, but not more than 4g in any 24 hour period, it’s relatively safe.

However, an overdose is extremely dangerous and is capable of causing serious damage to the liver and kidneys. Seek immediate medical advice.

There’s two modes of action Paracetamol uses. One is similar to NSAIDs (Non-Steroidal Anti Inflammatory Drugs) and stops the inflammation and the pain by blocking COX-2 receptors. This also links to the second mode of inhibiting Endocannabinoid reuptake within the brain.

Paracetamol is absorbed through the small intestine.

There’s been rarely any reports of side effects. But if there is an appearance of a rash, stop taking the medication.

You should speak with your GP or Pharmacist before using Paracetamol if you are currently taking anticoagulants like Warfarin.

Carbamazepine may increase the rate Paracetamol is metabolised.

Colestyramine reduces the absorption of Paracetamol and may effect it’s effectiveness.

Metoclopramide and Domperidone increase the rate Paracetamol is absorbed in the body.

Imatinib may interact with the Paracetamol and as such it is advisable to avoid altogether.

Published by Rochdalestu

I’m a 38 year old male who has recently been diagnosed with bipolar disorder. I have found it as a new chapter in my life that has opened my eyes to a whole new perspective on myself and everything around me.

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